ABSTRACT
Objective: To explore GRACE (global registry of acute coronary events)score on short term prognosis of ST-segment elevation myocardial infarction (STEMI)in patients elder than 75 years with primary percutaneous coronary intervention(PCI). Methods: A total of 104 STEMI patients elder than 75 years with primary PCI in our hospital from 2011-11 to 2014-01 were studied. Based on GRACEscore at admission, the patients were divided into 2 groups: Lower/mid risk group, n=72 patients with GRACEscore at 112-154 (136.5±10.6) and High risk group, n=32 patients with GRACE score at 155-202(167.8±12.3). The baseline condition and outcomes were compared between 2 groups and the primary endpoint was 1 year mortality. Predictive value of GRACEscore on 1 year mortality was evaluated by ROC curve, the relationships between Lower/mid risk group, High risk group and clinical outcomes were assessed by log-ranksurvive curve andunivariate Cox regression analysis. Results: The area under ROC curve for GRACEscore predicting 1 year mortality was 0.788 with the sensitivity at 70.0%and specificity at 84.0 %.Univariate Cox regression analysis indicated that compared with Lower/mid risk group, High risk group had the higher risk of 1-year death (HR=5.75, 95% CI 1.486-22.256, P=0.0113); log-rank survive curve presented that High risk group had the higher 1 year mortality (21.9% vs 4.2%, P=0.0039). Conclusion: GRACE score may further distinguish the lower/mid risk and high risk populations in elder STEMI patients; it may also predict 1 year clinical prognosis.
ABSTRACT
Objective To observe the clinical efficacy of moxibustion in treating knee osteoarthritis (KO) and analyze its cost-effectiveness.Method Fifty-eight KO patients were randomized into a moxibustion group and an electroacupuncture (EA) group, 29 cases in each group. The two groups were treated 3 times a week, for successive 4 weeks. The knee joint function and Visual Analogue Scale (VAS) for knee joint pain were scored before and after the treatment, and the two groups were analyzed by using health economic methods.Result The knee joint function scores were significantly changed after the treatment in the two groups (P<0.05); the excellent rate was 96.6％ in EA group versus 75.9％ in moxibustion group, and the general excellent rate in EA group was markedly higher than that in moxibustion group (P<0.05); the total effective rate for pain was 93.1％ in moxibustion group versus 96.6％ in EA group, and the between-group difference was statistically insignificant (P>0.05). The cost-effectiveness ratio was 6.42 in moxibustion group versus 16.86 in EA group; the incremental cost-effectiveness ratio was 298.55 in EA group. Conclusion Moxibustion and EA both can effectively improve knee joint function and mitigate knee joint pain, while compared with EA, moxibustion has a higher health economic value.
ABSTRACT
Objective To observe the clinical efficacy of moxibustion in treating knee osteoarthritis (KO) and analyze its cost-effectiveness.Method Fifty-eight KO patients were randomized into a moxibustion group and an electroacupuncture (EA) group, 29 cases in each group. The two groups were treated 3 times a week, for successive 4 weeks. The knee joint function and Visual Analogue Scale (VAS) for knee joint pain were scored before and after the treatment, and the two groups were analyzed by using health economic methods.Result The knee joint function scores were significantly changed after the treatment in the two groups (P<0.05); the excellent rate was 96.6％ in EA group versus 75.9％ in moxibustion group, and the general excellent rate in EA group was markedly higher than that in moxibustion group (P<0.05); the total effective rate for pain was 93.1％ in moxibustion group versus 96.6％ in EA group, and the between-group difference was statistically insignificant (P>0.05). The cost-effectiveness ratio was 6.42 in moxibustion group versus 16.86 in EA group; the incremental cost-effectiveness ratio was 298.55 in EA group. Conclusion Moxibustion and EA both can effectively improve knee joint function and mitigate knee joint pain, while compared with EA, moxibustion has a higher health economic value.